A second health worker in the US state of Texas has tested positive for Ebola, health officials say.
Both health workers treated Liberian man Thomas Duncan, who died last week after becoming the first person diagnosed with Ebola in the US.
A local judge said there was a "real possibility" of further cases, and contingencies were being prepared.
Meanwhile, the UN's Ebola mission chief says the world is falling behind in the race to contain the virus.
The World Health Organization (WHO) says 4,447 people have died from the outbreak, mainly in West Africa.
Sierra Leone, Liberia and Guinea have been hardest hit by the outbreak, which began in December 2013 but was confirmed in March.
President Barack Obama is due to hold a video conference with British, French, German and Italian leaders to discuss the Ebola crisis later on Wednesday.
'Not fearful'The identity of the second Texas health worker has not yet been revealed.
But Texas health officials said she was a woman who lived alone without pets, and was put in isolation within 90 minutes of her temperature being taken.
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How to remove a bodysuit after treating an Ebola patient
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The BBC's Alastair Leithead visited the National Biocontainment Training Centre in Galveston, Texas to try on a bio-hazard suit
Daniel Varga, the chief clinical officer of hospital operator Texas Health Resources, told a joint news conference that she was involved in the care of Mr Duncan and was exposed to the virus sometime during his treatment.
But Dallas County Judge Clay Jenkins said the authorities were preparing for more possible cases.
"We are preparing contingencies for more, and that is a very real possibility," he said.
Dallas mayor Mike Rawlings said it might take time to deal with the outbreak, but the authorities were "not fearful".
"We can only beat this moment by moment, person by person, detail by detail," he said at the news conference.
"It may get worse before it gets better, but it will get better."
Last weekend, officials announced nurse Nina Pham, 26, had been exposed to Ebola at a Dallas hospital when she treated Mr Duncan.
Doctors at the hospital said she was "doing well" on Tuesday.
By James Gallagher, BBC health editor
This is a reminder that Ebola is a dangerous threat even within some of the best hospitals in world.
This is the second case of transmission in Texas, on top of the case in Spain.
Protective gear should minimise the risk to health workers treating Ebola patients.
But worryingly there have been reports of staff not getting the correct equipment or the necessary training.
These isolated cases should not become an outbreak as authorities in both countries are monitoring those who came into contact with infected people.
But each new case of transmission is asking the question - is enough being done to protect healthcare workers?
US officials previously said they were monitoring 48 contacts of the Liberian national and the healthcare workers who treated him.
Mr Varga refused to comment on allegations from nurses at the Dallas hospital that health workers had been without adequate protective clothing for days during the outbreak. However, he said yes when asked if they had the necessary protective gear.
The nurses also alleged that they received little guidance on how to prevent the spread of the virus.
Ebola patients treated outside West Africa* Continue reading the main story*In all but three cases the patient was infected with Ebola while in West Africa. Infection outside Africa has been restricted to health workers in Madrid and in Dallas. DR Congo has also reported a separate outbreak of an unrelated strain of Ebola.
Continue reading the main storyHow not to catch Ebola:
- Avoid direct contact with sick patients as the virus is spread through contaminated body fluids
- Wear goggles to protect eyes
- Clothing and clinical waste should be incinerated and any medical equipment that needs to be kept should be decontaminated
- People who recover from Ebola should abstain from sex or use condoms for three months
Ebola basics: What you need to know
How Ebola attacks
Ebola: Mapping the outbreak
It comes after CDC chief Thomas Frieden said there had been a breach of protocol by health workers that led to the nurse becoming infected.
"The CDC is saying that protocols were breached, but the nurses are saying there were no protocols," the head of the national nurses union, Roseann DeMoro, told reporters on Tuesday.
There have been 8,914 Ebola cases overall, including the fatal cases, and the WHO says it expects this number to top 9,000 by the end of the week.
Anthony Banbury told a special session of the UN Security Council on Tuesday that if Ebola was not stopped now, the world would "face an entirely unprecedented situation for which we do not have a plan".
In other developments:
- Liberia's transport minister has gone into quarantine after her driver died from Ebola
- A football player for Sierra Leone's national team says his team-mates have been stigmatised and humiliated by the outbreak
- The World Health Organization (WHO) warns the infection rate could reach 5,000 to 10,000 new cases a week in two months if efforts are not stepped up
- The WHO says it will declare the end of the outbreak in Senegal at the end of this week (17 October) and in Nigeria next week (20 October), if no new cases are detected before then
The WHO estimates its figures by taking the numbers of confirmed cases and multiplying them - from Guinea by 1.5, from Sierra Leone by 2 and from Liberia by 2.5 - to account for under-reporting.
INTERACTIVE
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The cap forms part of a protective hood covering the head and neck. It offers medical workers an added layer of protection, ensuring that they cannot touch any part of their face whilst in the treatment centre.
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Goggles, or eye visors, are used to provide cover to the eyes, protecting them from splashes. The goggles are sprayed with an anti-fogging solution before being worn.
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Covers the mouth to protect from sprays of blood or body fluids from patients. When wearing a respirator, the medical worker must tear this outer mask to allow the respirator through.
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A respirator is worn to protect the wearer from a patient's coughs. According to guidelines from the medical charity Medecins Sans Frontieres (MSF), the respirator should be put on second, right after donning the overalls.
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A surgical scrub suit, durable hospital clothing that absorbs liquid and is easily cleaned, is worn as a baselayer underneath the overalls. It is normally tucked into rubber boots to ensure no skin is exposed.
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The overalls are placed on top of the scrubs. These suits are similar to hazardous material (hazmat) suits worn in toxic environments. The team member supervising the process should check that the equipment is not damaged.
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A minimum two sets of gloves are required, covering the suit cuff. When putting on the gloves, care must be taken to ensure that no skin is exposed and that they are worn in such a way that any fluid on the sleeve will run off the suit and glove. Medical workers must change gloves between patients, performing thorough hand hygiene before donning a new pair. Heavy duty gloves are used whenever workers need to handle infectious waste.
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A waterproof apron is placed on top of the overalls as a final layer of protective clothing.
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Ebola health workers typically wear rubber boots, with the scrubs tucked into the footwear. If boots are unavailable, workers must wear closed, puncture and fluid-resistant shoes.
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